Cleans GWAS summary statistics and adds metadata

RunCleaner(sumstats, ColsToKeep, bigSNP)

Arguments

sumstats

a tibble or data frame containing raw summary statistics. Coordinates should be hg39/b37; the pipeline does not support hg38.

ColsToKeep

character vector of the following columns: chr, position, allele1, allele2, beta, se, unique id, pvalue

Value

Cleaned summary statistics + LD block of every SNP, as well as its index in the reference panel of genotypes